In early sketches, I used a rough and ready style, and also provided a vector version. Vector art can be helpful in reproduction as it can scale to any size, from a pin badge to the side of a van.
In design apps, vector brushes can create very good clean line work, but I still find that they can't quite match the variation and liveliness of line work in pixel form, due to how software needs to process the data. Even converting pixels into vectors with the very best industry tools will smooth off lines and simplify them. I'm sure it won't be long before line work and speed of drawing is captured perfectly in pixels or vectors with no discernible difference, we're very nearly there. Saying that the software doesn't really matter, as long as the end product looks great.
This work was created in clip studio and the vectors in affinity designer. Affinity designer is super fast, but also Clip studio has the ability to export pixels in 4K and 600dpi resolution, which makes bigger files but keeps the aesthetic intact. Whatever gets the job done.